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Jacob S. Young, MD

Resident
UCSF
Charlottesville, Virginia, United States

Jacob (Jake) Young, MD is a PGY-5 neurosurgery resident at the University of California, San Francisco with an interest in neurosurgical oncology and immunotherapy. He is a graduate of Duke University and the University of Chicago Pritzker School of Medicine, where he was elected to the Phi Beta Kappa and Alpha Omega Alpha Honor Societies, respectively. In medical school, under the guidance of Maciej Lesniak MD, his translational research focused on designing and investigating novel viral and immunological agents for the treatment of high-grade gliomas. His research focuses on tumor-mediated immunosuppression in the context of glioma-neuronal functional remodeling, reprogramming the immunosuppressive glioma microenvironment, and the role of focused ultrasound in enhancing immunotherapy delivery. Additionally, he is interested in clinical trial development to translation discoveries in the laboratory to active clinical trials for patients at UCSF. He partners his laboratory work with clinical research exploring how to optimize functional outcomes and minimize complications after surgery for intrinsic brain tumors with direct electrical stimulation and brain mapping, where he works closely with mentors Shawn Hervey-Jumper MD, Manish Aghi MD PhD, and Mitchel Berger MD.

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